Greetwell Road in Lincoln will be closed overnight later this week as work takes place to repair and resurface the stretch of road.
Work will be carried out near to the pedestrian crossing and roundabout from 6pm on June 1, with the road expected to reopen at 6am on June 2.
Diversions will be via Outer Circle Road, Wragby Road and Queensway.
The one way system will also be revoked on Tower Drive with access to be gained from Tower Gardens rather than Greetwell Road.
A spokesperson for Lincolnshire County Council’s highways department said: “We are repairing and resurfacing this section of road as part of our routine maintenance programme.
“We apologise for any inconvenience this work may cause you.”