The Met Office issued an amber warning for snow across Lincolnshire on Friday, with more snow forecast for Saturday.
Snow is expected to extend Friday afternoon to much of northern and central England during the evening, clearing towards midnight.
Around 4 to 10 cm snowfall are likely within the amber warning area, with a low risk of more than 10 cm locally even on lower ground.
Strong winds will also lead to drifting and blizzard-like conditions, particularly over higher level roads.
Lighter snowfall in the form of a yellow warning from Met Office is forecast for Saturday, when 2-4 cm is likely in the south of the yellow warning area, with 4 to 8 cm over some hillier areas.
Forecasters are warning of possible disruption, particularly to travel.
On Sunday, heavy rain combined with snow melt could lead to localised surface water and river flooding.
Then from Monday, temperatures are expected to rise up to 8°C in Lincoln, and up to 12°C on Tuesday, when some rain is forecast. More details on our weather page.