Update 10.45am: The male pedestrian, who is said to have life-threatening injuries, was taken to hospital for treatment. The road was reopened at around midday.
A section of the A46 at Dunholme is closed this morning after a pedestrian was hit by a car.
The crash happened at about 7.19am at the junction with Ashing Lane and is believed to have involved a car and a male pedestrian.
The pedestrian has been taken to hospital for treatment and police say details are still being gathered in relation to his condition.
Emergency services including an air ambulance attended the scene.
The A46 and a number of surrounding areas will be closed and road users are being asked to avoid the area if possible, especially during rush hour traffic.
Anyone who witnessed the collision should contact the witness collision hotline 01522 558855 or the non-emergency number 101 quoting incident 53 ofJanuary 22.