Drivers are being warned of four weeks of overnight road closures on the A515 at Grimsthorpe near Bourne.
Work will begin on June 27 to reconstruct a 1,100m stretch of the carriageway from the Forstedd Hill junction eastwards.
The works should be completed within four weeks, weather permitting.
During the improvements, there will be an overnight road closure in place Monday to Friday, between the hours of 8pm and 6am, except on Friday, June 30 when no works will be taking place.
During the closure, traffic will be diverted via the A151, A1, B1174, A52 and A15.
Access will be maintained for residents, but there will be a speed limit of 10mph on site for safety.
A highways spokesperson from Lincolnshire County Council said: “This section of road has come to the end of its working life, so it’s essential we reconstruct it.
“We encourage motorists to allow additional time for their journeys while the work is taking place, and apologise for any inconvenience caused.”