The A16 bypass at Holton le Clay and its junction with the old Louth Road will be closed overnight due to resurfacing works lasting almost eight weeks.
On Monday, July 24, works will be undertaken to refurbish the junction, which will include new signals equipment, footway improvements and resurfacing and reconstruction of the carriageway.
During the works the old Louth Road will be closed at its junction with the A16 bypass on the north side of Holton le Clay.
All access to the old Louth Road and adjacent roads will be via the southern junction, near to the Jug and Bottle public house.
The improvements are expected to be completed by Friday, September 8.
Councillor Richard Davies, responsible for highways at Lincolnshire County Council, said: “This section of road is coming to the end of its life, so it’s essential we get it repaired.
“In order to minimise the disruption, some of the works will be carried out at night, so we can get it done as quickly as possible. However, the contractor will be required to keep the noise to a minimum.
“We’d recommend people allow extra time for their journeys while the work is taking place, and apologise for any inconvenience caused.”