Cross Keys Bridge, Sutton Bridge will be partly closed for a month of repairs, sparking warnings of significant disruption.
The resurfacing works will run from September 23 for four weeks, with preliminary work in the first week of the month.
Only one lane of the busy bridge will be open with traffic lights during the repairs, but drivers will be encouraged to go through a 32-mile diversion.
Lincolnshire County Council will have people working back to back shifts during to ensure that the repair is finished on time.
It has been over 10 years since the bridge’s surface has been replaced, so the road has been worn down extensively, the county council said.
They will be putting down a new skid resistant specialist surface to the tune of £100,000.
All marine traffic will be able to use the bridge as usual.
Karen Cassar, assistant director for highways at the council, said: “We’ve spoken to local residents, businesses and bus services about the project.
“They preferred to have the bridge open to two way traffic under traffic lights, in addition to a diversion route.
“We realise there will be significant disruption and severe delays in the area while the work is carried out.
“We’d like to reassure residents that will do all we can to reduce the disruption, and get the work completed as quickly as possible.”