Lincolnshire County Council will be using Waddington to test local emergency services and other public sector organisations in a serious incident.
The exercise, as part of Exercise Georgiana, will take place on May 21 and 22 just off the A15 to test the council’s large scale emergency plans.
It aims to test personnel and systems of contingencies in coping, containing and resolving a major incident.
The exercise will involve services such as Lincolnshire Police, Lincolnshire Fire and Rescue, East Midlands Ambulance Service, local authorities, the Environment Agency and health agencies, plus voluntary and private agencies.
The council said the exercise will not disrupt the public, but motorists may see more emergency vehicles in the area.
The exercise runs between 8am and 9pm.