Emergency services and the air ambulance attended a two car crash on A158 Wragby Road near the roundabout with the A15.
There are long delays while police investigate this evening and the road is partially closed.
Firefighters had to cut out victims from the wreckage after the crash was reported just before 4.30pm.
Queues are along Bunkers Hill and the A15. Police advise to use local diversion routes.