There will be up to seven weeks of disruption as work begins to build a new puffin crossing in Wragby.
The works on the A158, between the mini roundabout to the west of Manor Drive, will start on Monday, October 12.
This will be followed by a new zebra crossing in early 2021.
Other improvements will be made to this stretch of carriageway including rebuilding a section of the road and pavement, improving signage and road lining, and replacing street lights.
Temporary traffic signals will be in place 24 hours a day, Monday to Friday, until Tuesday, November 24.
There will also be a 24/7 road closure of Silver Street, with a diversion route via A157 Louth Road/A158 Church Road.
This will be followed by four evenings of night-time road closures on the A158 starting on November 24 for road reconstruction works from 7pm to 5am.
The diversion route for this will be via Wragby roundabout/A157 Louth Road/B1225 High Street/southbound to Hunters Lane/A158, and vice versa.
Councillor Patricia Bradwell OBE, Deputy Leader and County Councillor for Woodhall Spa & Wragby, said: “Residents have been calling for a pedestrian crossing here for years, and I’m really happy to say we can now make it happen.
“Once these works are complete, the A158 will be much safer for children and adults wanting to cross it.
“And early next year, we’ll be making our roads even safer for pedestrians when a new zebra crossing is installed on the A157 in Wragby.”
Councillor Richard Davies, executive member for highways, said: “In addition to the A158 in Wragby, we’re also making major improvements to the A46 near Welton and Dunholme and at Riseholme Roundabout; A52 Roman Bank in Skegness; and A631 between Louth and Market Rasen.
“We’re also replacing guardrails and concrete slabs, surfacing and patching sections of carriageway and improving road markings along many of routes people use to reach our coast.”